The administration of hyaluronidase, an enzyme that breaks down hyaluronic acid, is a common procedure to reverse the effects of hyaluronic acid-based dermal fillers. The duration for complete dissolution varies significantly based on several factors. These include the type and concentration of the filler used, the amount of hyaluronidase injected, the individual’s metabolism, and the location of the filler.
Hyaluronidase offers a valuable option for correcting overfilled areas, addressing asymmetry, or resolving complications such as vascular occlusion caused by filler injections. Historically, hyaluronidase was primarily used in ophthalmology and as a spreading agent for other medications. Its application in aesthetic medicine has become increasingly prevalent as the use of dermal fillers has grown, providing a safety net for managing unwanted outcomes.